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3 associated genes
4 signs/symptoms
PROTEIN INTERACTIONS: 1
1 OMIM reference -
2 associated genes
13 signs/symptoms
Well-differentiated liposarcoma
Systemic-onset juvenile idiopathic arthritis

CDK4 IL6
HMGA2 MIF
MDM2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
MDM2
(0.63)
MIF



Citations in the biomedical literature:


Well-differentiated liposarcoma
CDK4 HMGA2 MDM2
Systemic-onset juvenile idiopathic arthritis
IL6 MIF



Well-differentiated liposarcoma
Systemic-onset juvenile idiopathic arthritis

Synonym(s):
- ALT
- Atypical lipoma
- Atypical lipomatous tumor
- WDLS

Synonym(s):
- Still disease
- Systemic polyarthritis

Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
- Rare respiratory disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -

Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: normal
Type of inheritance: unknown

External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
No MeSH references

Well-differentiated liposarcoma
Systemic-onset juvenile idiopathic arthritis

Very frequent
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma
- Subcutaneous nodules / lipomas / tumefaction / swelling

Occasional
- Functional anomalies of the kidney and the urinary tract
- Intestinal transit disorder


Very frequent
- Arthritis / synovitis / synovial proliferation
- Articular / joint pain / arthralgia
- Autoimmunity / autoimmune reaction / autoantibodies
- Biological inflammatory syndrome / increased erythrocyte sedimentation rate / CRP
- Cutaneous rash
- Fever / chilling
- Hydrarthrosis / articular / joint effusion

Frequent
- Mediastinal / hilar adenopathies

Occasional
- Abnormal pleura / hydrothorax / pleuresia / pleural effusion / chylothorax
- Acute abdominal pain / colic
- Hepatomegaly / liver enlargement (excluding storage disease)
- Pericardium anomalies / pericarditis / absence / cysts / pericardial effusion
- Splenomegaly